Fatigue while on Cymbalta?

Sometimes that's an initial side effect. If you find that Cymbalta keeps you awake and then makes you crash, make sure to take if first thing in the morning. If you find yourself up for more than a day, you can try natural herbal supplements like Melatonin And Valerian Root. I've found Valerian supplements whether in pill or tea form have been very helpful with insomnia caused by medication. If you decide to try them, make sure to discuss it with your doctor as some herbal supplements can counteract with medications.